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1

Sickle-cell disease

David C Rees, Thomas N Williams, Mark T Gladwin

Journal:

Year:

2010

Language:

english

File:

PDF, 1.36 MB

english, 2010

2

Carbon Monoxide Poisoning: Pathogenesis, Management and Future Directions of Therapy

Rose, Jason J, Wang, Ling, Xu, Qinzi, McTiernan, Charles F, Shiva, Sruti, Tejero, Jesus, Gladwin, Mark T

Journal:

American Journal of Respiratory and Critical Care Medicine

Year:

2016

Language:

english

File:

PDF, 945 KB

english, 2016

3

Pathophysiology of Sickle Cell Disease

Sundd, Prithu, Gladwin, Mark T., Novelli, Enrico M.

Journal:

Annual Review of Pathology Mechanisms of Disease

Year:

2019

Language:

english

File:

PDF, 2.59 MB

english, 2019

4

The hydrogen highway to reperfusion therapy

Wood, Katherine C, Gladwin, Mark T

Journal:

Nature Medicine

Year:

2007

Language:

english

File:

PDF, 825 KB

english, 2007

5

Biomarker signatures of sickle cell disease severity

Du, Mengtian, Van Ness, Sarah, Gordeuk, Victor, Nouraie, Sayed M., Nekhai, Sergei, Gladwin, Mark, Steinberg, Martin H., Sebastiani, Paola

Journal:

Blood Cells, Molecules, and Diseases

Year:

2018

Language:

english

File:

PDF, 2.17 MB

english, 2018

6

Cerebrovascular disease associated with sickle cell pulmonary hypertension

Gregory J. Kato, Matthew Hsieh, Roberto Machado, James Taylor VI, Jane Little, John A. Butman, Tanya Lehky, John Tisdale, Mark T. Gladwin

Journal:

American Journal of Hematology

Year:

2006

Language:

english

File:

PDF, 191 KB

english, 2006

7

The emerging biology of the nitrite anion

Gladwin, Mark T, Schechter, Alan N, Kim-Shapiro, Daniel B, Patel, Rakesh P, Hogg, Neil, Shiva, Sruti, Cannon, Richard O, Kelm, Malte, Wink, David A, Espey, Michael Graham

Journal:

Nature Chemical Biology

Year:

2005

Language:

english

File:

PDF, 496 KB

english, 2005

8

Nitric oxide's reactions with hemoglobin: a view through the SNO-storm

Gladwin, Mark T., Lancaster, Jack R., Freeman, Bruce A., Schechter, Alan N.

Journal:

Nature Medicine

Year:

2003

Language:

english

File:

PDF, 374 KB

english, 2003

9

The nitrate–nitrite–nitric oxide pathway in physiology and therapeutics

Lundberg, Jon O., Weitzberg, Eddie, Gladwin, Mark T.

Journal:

Nature Reviews Drug Discovery

Year:

2008

Language:

english

File:

PDF, 2.19 MB

english, 2008

10

Downsides to the nitrate–nitrite–nitric oxide pathway in physiology and therapeutics? Reply from Lundberg, Weitzberg and Gladwin

Lundberg, Jon O., Weitzberg, Eddie, Gladwin, Mark T.

Journal:

Nature Reviews Drug Discovery

Year:

2008

Language:

english

File:

PDF, 116 KB

english, 2008

11

Emerging role of nitrite in human biology

André Dejam, Christian J Hunter, Alan N Schechter, Mark T Gladwin

Journal:

Blood Cells, Molecules, and Diseases

Year:

2004

Language:

english

File:

PDF, 258 KB

english, 2004

12

Updated Clinical Classification of Pulmonary Hypertension

Gérald Simonneau, Ivan M. Robbins, Maurice Beghetti, Richard N. Channick, Marion Delcroix, Christopher P. Denton, C. Gregory Elliott, Sean P. Gaine, Mark T. Gladwin, Zhi-Cheng Jing, Michael J. Krowka,

Journal:

Journal of the American College of Cardiology

Year:

2009

Language:

english

File:

PDF, 407 KB

english, 2009

13

A pilot study of electronic directly observed therapy to improve hydroxyurea adherence in pediatric patients with sickle-cell disease

Creary, Susan E., Gladwin, Mark T., Byrne, Melissa, Hildesheim, Mariana, Krishnamurti, Lakshmanan

Journal:

Pediatric Blood & Cancer

Year:

2014

Language:

english

File:

PDF, 134 KB

english, 2014

14

Strategies to increase nitric oxide signalling in cardiovascular disease

Lundberg, Jon O., Gladwin, Mark T., Weitzberg, Eddie

Journal:

Nature Reviews Drug Discovery

Year:

2015

Language:

english

File:

PDF, 1.72 MB

english, 2015

15

Arginine Metabolism and Nitric Oxide Bioavailability in Sickle Cell Disease

Jain, Shilpa, Gladwin, Mark T.

Journal:

Journal of Pediatric Hematology/Oncology

Year:

2010

Language:

english

File:

PDF, 62 KB

english, 2010

16

EXPRESS: Experimental Intravascular Hemolysis Induces Hemodynamic and Pathological Pulmonary Hypertension – Association with Accelerated Purine Metabolism

Bilan, Victor, Schneider, Frank, Novelli, Enrico M., Kelley, Eric E., Sriva, Sruti, Gladwin, Mark, Jackson, Edwin K, Tofovic, Stevan P

Journal:

Pulmonary Circulation

Year:

2018

Language:

english

File:

PDF, 2.11 MB

english, 2018

17

Intravascular hemolysis and the pathophysiology of sickle cell disease

Kato, Gregory J., Steinberg, Martin H., Gladwin, Mark T.

Journal:

The Journal of clinical investigation

Year:

2017

Language:

english

File:

PDF, 899 KB

english, 2017

18

Improved quantitative detection of biotin‐labeled red blood cells by flow cytometry

Donnenberg, Albert D., Kanias, Tamir, Triulzi, Darrell J., Dennis, Catherine J., Meyer, E. Michael, Gladwin, Mark

Journal:

Transfusion (Wiley)

Year:

2019

Language:

english

File:

PDF, 691 KB

english, 2019

19

Relative systemic hypertension in patients with sickle cell disease is associated with risk of pulmonary hypertension and renal insufficiency

Victor R. Gordeuk, Vandana Sachdev, James G. Taylor, Mark T. Gladwin, Gregory Kato, Oswaldo L. Castro

Journal:

American Journal of Hematology

Year:

2008

Language:

english

File:

PDF, 161 KB

english, 2008

20

Mutations and polymorphisms in hemoglobin genes and the risk of pulmonary hypertension and death in sickle cell disease

James G. Taylor VI, Diana Ackah, Crystal Cobb, Nick Orr, Melanie J. Percy, Vandana Sachdev, Roberto Machado, Oswaldo Castro, Gregory J. Kato, Stephen J. Chanock, Mark T. Gladwin

Journal:

American Journal of Hematology

Year:

2008

Language:

english

File:

PDF, 371 KB

english, 2008

21

Severe pulmonary hypertension in an adolescent with sickle cell disease

James G. Taylor VI, Gerald M. Woods, Roberto Machado, Gregory J. Kato, Mark T. Gladwin

Journal:

American Journal of Hematology

Year:

2008

Language:

english

File:

PDF, 174 KB

english, 2008

22

Sickle cell disease and pulmonary hypertension in Africa: A global perspective and review of epidemiology, pathophysiology, and management

Zakari Y. Aliyu, Gregory J. Kato, James Taylor IV, Aliyu Babadoko, Aisha I. Mamman, Victor R. Gordeuk, Mark T. Gladwin

Journal:

American Journal of Hematology

Year:

2008

Language:

english

File:

PDF, 203 KB

english, 2008

23

Vasculopathy in sickle cell disease: Biology, pathophysiology, genetics, translational medicine, and new research directions

Gregory J. Kato, Robert P. Hebbel, Martin H. Steinberg, Mark T. Gladwin

Journal:

American Journal of Hematology

Year:

2009

Language:

english

File:

PDF, 220 KB

english, 2009

24

Plasma thrombospondin-1 is increased during acute sickle cell vaso-occlusive events and associated with acute chest syndrome, hydroxyurea therapy, and lower hemolytic rates

Enrico M Novelli, Gregory J. Kato, Margaret V. Ragni, Yingze Zhang, Mariana E. Hildesheim, Mehdi Nouraie, Suchitra Barge, Michael P. Meyer, Andrea Cortese Hassett, Victor R. Gordeuk, Mark T. Gladwin,

Journal:

American Journal of Hematology

Year:

2012

Language:

english

File:

PDF, 445 KB

english, 2012

25

Hemoglobin as a Nitrite Anhydrase: Modeling Methemoglobin-Mediated N2O3 Formation

Dr. Kathrin H. Hopmann, Dr. Bruno Cardey, Prof. Mark T. Gladwin, Prof. Daniel B. Kim-Shapiro, Prof. Abhik Ghosh

Journal:

Chemistry - A European Journal

Year:

2011

Language:

english

File:

PDF, 1.10 MB

english, 2011

26

Cover Picture: Hemoglobin as a Nitrite Anhydrase: Modeling Methemoglobin-Mediated N2O3 Formation (Chem. Eur. J. 23/2011)

Dr. Kathrin H. Hopmann, Dr. Bruno Cardey, Prof. Mark T. Gladwin, Prof. Daniel B. Kim-Shapiro, Prof. Abhik Ghosh

Journal:

Chemistry - A European Journal

Year:

2011

Language:

english

File:

PDF, 1.02 MB

english, 2011

27

Nitric Oxide (NO) in normal and hypoxic vascular regulation of the spiny dogfish, Squalus acanthias

Kai E. Swenson, Randy L. Eveland, Mark T. Gladwin, Erik R. Swenson

Journal:

Journal of Experimental Zoology Part A Ecological Genetics and Physiology

Year:

2005

Language:

english

File:

PDF, 96 KB

english, 2005

28

Deconstructing sickle cell disease: Reappraisal of the role of hemolysis in the development of clinical subphenotypes

Gregory J. Kato, Mark T. Gladwin, Martin H. Steinberg

Journal:

Year:

2007

Language:

english

File:

PDF, 634 KB

english, 2007

29

Measurement of circulating nitrite and S-nitrosothiols by reductive chemiluminescence

Peter H. MacArthur, Sruti Shiva, Mark T. Gladwin

Journal:

Journal of Chromatography B

Year:

2007

Language:

english

File:

PDF, 657 KB

english, 2007

30

Effect of nitric oxide and nitric oxide donors on red blood cell oxygen transport

Borys W. Hrinczenko, Abdu I. Alayash, David A. Wink, Mark T. Gladwin, Griffin P. Rodgers, Alan N. Schechter

Journal:

British Journal of Haematology

Year:

2000

Language:

english

File:

PDF, 307 KB

english, 2000

31

Nitric oxide donor properties of hydroxyurea in patients with sickle cell disease

Mark T. Gladwin, James H. Shelhamer, Frederick P. Ognibene, Margaret E. Pease-Fye, James S. Nichols, Beth Link, Daksesh B. Patel, Marcin A. Jankowski, Lewis K. Pannell, Alan N. Schechter, Griffin P. R

Journal:

British Journal of Haematology

Year:

2002

Language:

english

File:

PDF, 288 KB

english, 2002

32

Nitrite mediates cytoprotection after ischemia/reperfusion by modulating mitochondrial function

Sruti Shiva, Mark T. Gladwin

Journal:

Basic Research in Cardiology

Year:

2009

Language:

english

File:

PDF, 209 KB

english, 2009

33

The reaction between nitrite and hemoglobin: the role of nitrite in hemoglobin-mediated hypoxic vasodilation

Daniel B. Kim-Shapiro, Mark T. Gladwin, Rakesh P. Patel, Neil Hogg

Journal:

Journal of Inorganic Biochemistry

Year:

2005

Language:

english

File:

PDF, 393 KB

english, 2005

34

Chronic sickle cell lung disease: new insights into the diagnosis, pathogenesis and treatment of pulmonary hypertension

Roberto F. Machado, Mark T. Gladwin

Journal:

British Journal of Haematology

Year:

2005

Language:

english

File:

PDF, 539 KB

english, 2005

35

Levels of soluble endothelium-derived adhesion molecules in patients with sickle cell disease are associated with pulmonary hypertension, organ dysfunction, and mortality

Gregory J. Kato, Sabrina Martyr, William C. Blackwelder, James S. Nichols, Wynona A. Coles, Lori A. Hunter, Marie-Luise Brennan, Stanley L. Hazen, Mark T. Gladwin

Journal:

British Journal of Haematology

Year:

2005

Language:

english

File:

PDF, 205 KB

english, 2005

36

Severity of pulmonary hypertension during vaso-occlusive pain crisis and exercise in patients with sickle cell disease

Roberto F. Machado, A. Kyle Mack, Sabrina Martyr, Christopher Barnett, Peter MacArthur, Vandana Sachdev, Inez Ernst, Lori A. Hunter, Wynona A. Coles, James P. Nichols, Gregory J. Kato, Mark T. Gladwin

Journal:

British Journal of Haematology

Year:

2007

Language:

english

File:

PDF, 577 KB

english, 2007

37

Mixed haematopoietic chimerism for sickle cell disease prevents intravascular haemolysis

Catherine J. Wu, Mark Gladwin, John Tisdale, Matthew Hsieh, Terence Law, Melinda Biernacki, Shelby Rogers, Xunde Wang, Mark Walters, David Zahrieh, Joseph H. Antin, Jerome Ritz, Lakshamanan Krishnamur

Journal:

British Journal of Haematology

Year:

2007

Language:

english

File:

PDF, 142 KB

english, 2007

38

Sodium nitrite promotes regional blood flow in patients with sickle cell disease: a phase I/II study

A. Kyle Mack, Vicki R. McGowan II, Carole K. Tremonti, Diana Ackah, Christopher Barnett, Roberto F. Machado, Mark T. Gladwin, Gregory J. Kato

Journal:

British Journal of Haematology

Year:

2008

Language:

english

File:

PDF, 167 KB

english, 2008

39

Prospective evaluation of haemoglobin oxygen saturation at rest and after exercise in paediatric sickle cell disease patients

Andrew Campbell, Caterina P. Minniti, Mehdi Nouraie, Manuel Arteta, Sohail Rana, Onyinye Onyekwere, Craig Sable, Gregory Ensing, Niti Dham, Lori Luchtman-Jones, Gregory J. Kato, Mark T. Gladwin, Oswal

Journal:

British Journal of Haematology

Year:

2009

Language:

english

File:

PDF, 105 KB

english, 2009

40

Endothelin receptor antagonists for pulmonary hypertension in adult patients with sickle cell disease

Caterina P. Minniti, Roberto F. Machado, Wynona A. Coles, Vandana Sachdev, Mark T. Gladwin, Gregory J. Kato

Journal:

British Journal of Haematology

Year:

2009

Language:

english

File:

PDF, 96 KB

english, 2009

41

Effect of eculizumab on haemolysis-associated nitric oxide depletion, dyspnoea, and measures of pulmonary hypertension in patients with paroxysmal nocturnal haemoglobinuria

Anita Hill, Russell P. Rother, Xunde Wang, Sidney M. Morris, Jr, Kerry Quinn-Senger, Richard Kelly, Stephen J. Richards, Monica Bessler, Leonard Bell, Peter Hillmen, Mark T. Gladwin

Journal:

British Journal of Haematology

Year:

2010

Language:

english

File:

PDF, 538 KB

english, 2010

42

Exercise capacity and haemodynamics in patients with sickle cell disease with pulmonary hypertension treated with bosentan: results of the ASSET studies

Robyn J. Barst, Kamal K. Mubarak, Roberto F. Machado, Kenneth I. Ataga, Raymond L. Benza, Oswaldo Castro, Robert Naeije, Namita Sood, Paul S. Swerdlow, Mariana Hildesheim, Mark T. Gladwin, on behalf o

Journal:

British Journal of Haematology

Year:

2010

Language:

english

File:

PDF, 433 KB

english, 2010

43

Association of G6PD202A,376G with lower haemoglobin concentration but not increased haemolysis in patients with sickle cell anaemia

Mehdi Nouraie, Noel S. Reading, Andrew Campbell, Caterina P. Minniti, Sohail R. Rana, Lori Luchtman-Jones, Gregory J. Kato, Mark T. Gladwin, Oswaldo L. Castro, Josef T. Prchal, Victor R. Gordeuk

Journal:

British Journal of Haematology

Year:

2010

Language:

english

File:

PDF, 184 KB

english, 2010

44

NT-proBNP as a marker of cardiopulmonary status in sickle cell anaemia in Africa

Zakari Y. Aliyu, Aisha Suleiman, Ester Attah, Aisha I. Mamman, Aliyu Babadoko, Mehdi Nouraie, Laurel Mendelsohn, Gregory J. Kato, Victor R. Gordeuk, Mark T. Gladwin

Journal:

British Journal of Haematology

Year:

2010

Language:

english

File:

PDF, 211 KB

english, 2010

45

NT-pro brain natriuretic peptide levels and the risk of death in the cooperative study of sickle cell disease

Roberto F. Machado, Mariana Hildesheim, Laurel Mendelsohn, Alan T. Remaley, Gregory J. Kato, Mark T. Gladwin

Journal:

British Journal of Haematology

Year:

2011

Language:

english

File:

PDF, 213 KB

english, 2011

46

Senicapoc trial results support the existence of different sub-phenotypes of sickle cell disease with possible drug-induced phenotypic shifts

Oswaldo L. Castro, Victor R. Gordeuk, Mark T. Gladwin, Martin H. Steinberg

Journal:

British Journal of Haematology

Year:

2011

Language:

english

File:

PDF, 65 KB

english, 2011

47

Methaemalbumin formation in sickle cell disease: effect on oxidative protein modification and HO-1 induction

Madelyn S. Hanson, Barbora Piknova, Agnes Keszler, Anne R. Diers, Xunde Wang, Mark T. Gladwin, Cheryl A. Hillery, Neil Hogg

Journal:

British Journal of Haematology

Year:

2011

Language:

english

File:

PDF, 446 KB

english, 2011

48

Storage lesion: role of red blood cell breakdown

Daniel B. Kim-Shapiro, Janet Lee, Mark T. Gladwin

Journal:

Transfusion (Wiley)

Year:

2011

Language:

english

File:

PDF, 308 KB

english, 2011

49

Nitrate and nitrite in biology, nutrition and therapeutics

Lundberg, Jon O, Gladwin, Mark T, Ahluwalia, Amrita, Benjamin, Nigel, Bryan, Nathan S, Butler, Anthony, Cabrales, Pedro, Fago, Angela, Feelisch, Martin, Ford, Peter C

Journal:

Nature Chemical Biology

Year:

2009

Language:

english

File:

PDF, 449 KB

english, 2009

50

Corrigendum: The emerging biology of the nitrite anion

Gladwin, Mark T, Schechter, Alan N, Kim-Shapiro, Daniel B, Patel, Rakesh P, Hogg, Neil, Shiva, Sruti, Cannon, Richard O, Kelm, Malte, Wink, David A, Espey, Michael Graham

Journal:

Nature Chemical Biology

Year:

2006

File:

PDF, 52 KB

2006